What is the difference between PRN and STAT medications?

• A. PRN meds are given as needed; STAT meds are given immediately for urgent need.
• B. PRN meds are given only after a physician signs off; STAT meds are given on a fixed schedule.
• C. PRN meds require pharmacy review; STAT meds require nurse initiation.
• D. PRN meds are given immediately for urgent needs; STAT meds are given as needed.

Answer: (B)

The difference hinges on timing and purpose. PRN medications are given as needed, based on the patient’s symptoms or requests and within the limits of the prescribed order (dose, frequency). The nurse uses judgment to decide when relief is warranted, not on a fixed schedule. STAT medications are for urgent, time-sensitive situations and must be given immediately once the order is received, to address a critical condition.

So PRN means “as needed” and relies on assessment and symptom relief, while STAT means “immediately” and is used for urgent needs. The other options mix up who initiates or when the meds are given and aren’t consistent with how PRN and STAT orders are intended to function.